The ICIC 2026 International Cosmetic Innovation Conference concluded successfully! As the premier global event for beauty research and industrial innovation, the conference brought together leading suppliers, top-tier research institutions, authoritative dermatology experts, and mainstream brands to focus on core topics such as cosmetic technology innovation, efficacy-driven skincare, and precision anti-aging, fostering discussions on the future of the industry.
Changsha Luocheng Trading Co., Ltd. made a remarkable debut with its cutting-edge peptide research achievements. The oligopeptide SkinPep®OP 017SL stood out among hundreds of candidate ingredients thanks to its advanced gene-level anti-aging technology, earning the ICIC Technology Innovation Outstanding Raw Material Award. More significantly, Paite Biotech participated in the conference’s authoritative Skin Anti-Aging Frontier Forum, delivering a keynote speech titled “Peptides Empower Gene-Level Anti-Aging Solutions.” Through in-depth scientific research and empirical data, the presentation comprehensively elucidated the core mechanisms and clinical applications of oligopeptide-6, capturing widespread attention at the event.

During the exhibition, the booth of Paite Biotech remained bustling with visitors, becoming one of the focal points of the event. The R&D and business teams conducted in-depth exchanges with global brand owners, research institutions, and distributors through professional presentations and meticulous services, facilitating on-site discussions on potential collaborations. Their efforts earned high recognition and unanimous praise from industry peers.

1.Photodamage and Oxidative Stress: The “Accelerator” of Skin Aging

The destructive pathways of ultraviolet (UV) radiation: UVB directly damages epidermal cell DNA, inducing thymine dimer formation and leading to genetic mutations; UVA penetrates the dermis, where it generates reactive oxygen species (ROS) that damage collagen and elastic fibers, resulting in wrinkles and skin laxity.
The vicious cycle of oxidative stress: Increased oxidative stress leads to a rise in free radicals, with the accumulation of ROS inhibiting mitochondrial function, thereby further amplifying free radical generation and triggering an “oxidative storm.” This results in accelerated collagen degradation, reduced synthesis, decreased skin elasticity, and accelerated aging.

(1). DNA Damage: The “Root Cause” of Aging: UV radiation can directly or indirectly cause DNA damage. In keratinocytes, DNA directly absorbs the wavelengths emitted by UVB, leading to various types of damage, such as disruption of the DNA double-stranded structure, DNA strand breaks, and excision or substitution of bases or base pairs. With advancing age, DNA damage accumulates, telomeres shorten, cellular division capacity declines, and cellular functions deteriorate, ultimately triggering skin aging and inflammatory responses.
(2). Abnormal energy metabolism: Cellular “power failure” and abnormal energy metabolism: In senescent cells, the mitochondrial membrane potential decreases, ATP production reduces by 30%-50%, while ROS leakage increases, resulting in a “low-energy-high-consumption” state. Mitochondrial dysfunction leads to abnormal energy metabolism, reduced cellular viability, impaired skin barrier function, and increased wrinkle formation.

Comprehensive Review of the Exhibition: During the event, the booth of Paite Biotech remained bustling with visitors, standing out as one of the highlights. The R&D and business teams delivered professional presentations and meticulous services, engaging in in-depth discussions with global brand owners, research institutions, and distributors. On-site collaboration negotiations were conducted, earning high recognition and unanimous praise from industry peers.

Changsha Luocheng Trading Co., Ltd. is a specialized supplier of high-purity peptides for the cosmetic, wellness, and fitness industries. Our core products include cosmetic peptides, anti-aging peptides, weight management peptides, and muscle-building peptides – serving skincare brands, supplement formulators, and health-focused companies worldwide.